Well there is absolutely no biological evidence to suggest otherwise. No matter what anyone feels in the inside we all either have xx or su chromosomes. No such thing as a z chromosome. That not only determines your sex but also gender. If there were multiple genders it would be very noticeable. It’s obvious that to transform yourself into a gender that doesn’t exist is completely unatural and inhumane which is why the transgender suicide rates are so high and it does not get better after surgery of any kind.
And besides all that, to have man and woman was God’s original plan for humanity.